Important Safety Information

Important Safety Information

What is the most important safety information I should know about TLANDO?

Blood Pressure Increases – TLANDO can increase blood pressure, which can increase the risk of having a heart attack or stroke and can increase your risk of death due to a heart attack or stroke. Your risk may be greater if you have already had a heart attack or stroke or if you have other risk factors for heart attack or stroke.

If your blood pressure increases while you are on TLANDO, blood pressure medicines may need to be started or new medicines may need to be added. If your blood pressure cannot be controlled, TLANDO may need to be stopped. Your healthcare provider should monitor your blood pressure while you are being treated with TLANDO.

What is TLANDO?

TLANDO is a prescription medicine that contains testosterone. TLANDO is used to treat adult men who have low or no testosterone due to certain medical conditions.

It is not known if TLANDO is safe and effective for use in children younger than 18 years old. Improper use of TLANDO may effect bone growth in children.

TLANDO is a controlled substance (CIII) because it contains testosterone that can be a target for people who abuse prescription medicines. Keep your TLANDO in a safe place to protect it. Never give your TLANDO to anyone else. Selling or giving away this medicine may harm others and it is against the law.

TLANDO is not meant for use by women.

Do not use TLANDO if you:

• Are a man who has breast cancer.
• Have or might have prostate cancer.
• Are a woman who is pregnant. TLANDO may harm your unborn baby.
• Are allergic to TLANDO or to any TLANDO ingredients.
• Have low testosterone without certain medical conditions. For example, do not take TLANDO if you have low testosterone due to age.

What should I tell my healthcare provider before using TLANDO?

Before you use TLANDO, tell your healthcare provider about all of your medical conditions, including, if you experience any of the following: high blood pressure or heart problems, high red blood cell count, urinary problems due to an enlarged prostate, kidney or liver problems, problems breathing while you sleep (sleep apnea) and enlarged or painful breasts.

Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Using TLANDO with other medicines can affect each other. Especially, tell your healthcare provider if you take insulin, medicines that decrease blood clotting (blood thinners), corticosteroids or medicines for pain and cold. Know the medicines you take. Ask your pharmacist for a list of all your medicines if you are not sure. Show your list to your healthcare provider and pharmacist when you get a new medicine.

How should I use TLANDO?

Use TLANDO exactly as your healthcare provider tells you to take it.

What are the possible side effects of TLANDO?

TLANDO can cause serious side effects including:

• See “What is the most important information I should know about TLANDO?” above.
• Blood pressure increases. TLANDO can increase blood pressure, which can increase the risk of having a heart attack or stroke and can increase your risk of death due to a heart attack or stroke.
• Increase in red blood cell count, hematocrit or hemoglobin. High red blood cell counts increase the risk of clots, strokes, and heart attacks. You may need to stop TLANDO if your red blood cell count increases. Your healthcare provider should check your red blood cell count, hematocrit and hemoglobin while you use TLANDO.
• Cardiovascular risk. Possible increased risk of heart attack, death, or stroke.
• If you already have an enlarged prostate, your signs and symptoms may get worse while using TLANDO. This can include: increased nighttime urination,trouble starting urination, more frequent urination, feeling an urge to urinate, having a urine accident, and being unable to pass urine or weak urine flow
• Increased risk of prostate cancer. Your healthcare provider should check you for prostate cancer or any other prostate problems before you start and while you use TLANDO.
• Blood clots in the legs or lungs. Signs and symptoms of a blood clot in your leg can include leg pain, swelling or redness. Signs and symptoms of a blood clot in your lungs can include difficulty breathing or chest pain.
• Abuse. Testosterone can be abused, when taken at higher than prescribed doses and when used with other anabolic androgenic steroids. Abuse can cause serious heart and psychological side effects.
• In large doses TLANDO may lower your sperm count.
• Liver problems. Symptoms of liver problems may include nausea or vomiting, yellowing of your skin or whites of your eyes, dark urine or pain on the right side of your stomach area (abdominal pain).
• Swelling of your ankles, feet, or body, with or without heart failure. This may cause serious problems for people who have heart, kidney or liver disease.
• Problems breathing while you sleep (sleep apnea).
• Enlarged or painful breasts.

Call your healthcare provider right away if you have any of the serious side effects listed above.

The most common side effects of TLANDO include: increased blood prolactin, increased blood pressure, red blood cell increase, upper respiratory tract infection, weight increased, headache, and musculoskeletal pain.

For more information, go to www.TLANDO.com or call 1-844-996-7833.

To report side effects to the FDA visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see the full Prescribing Information, including Boxed Warning, and Medication Guide.